Clinical Trials

Clinical trials help improve cancer care by evaluating new treatments, new combinations of existing treatments, and other approaches to preventing, diagnosing, or managing cancer. Our research team works closely with your treating physician to determine whether a clinical trial may be an appropriate option for you.

Participation is always voluntary

For more information about trials available in our site, please contact our research team at
research@venturaoncology.com or 805-485-8709 extension 129.

Currently Recruiting Clinical Trials

The studies below are currently open to enrollment at our practice. Eligibility depends on each study’s specific requirements and your individual medical history.

  1. Study: A clinical trial for individuals who have been diagnosed with advanced or metastatic HR+/HER2- breast cancer and have NOT received any prior systemic therapy for advanced or metastatic HR+/HER2- breast cancer
    Cancer Type: Breast Cancer
    Study Type/Phase: Interventional / Phase 3
    Principal Investigator: Dr. Chirag Dalsania M.D.

    About this study:
    The purpose of this study is to investigate the efficacy and safety of BGB-43395 in combination with letrozole compared with investigator's choice of cyclin-dependent kinase 4/6 inhibitor (CDK4/6i) in combination with letrozole in patients with advanced or metastatic hormone receptor positive (HR+)/human epidermal growth factor receptor 2 negative (HER2-) breast cancer (BC) who have not received prior systemic treatment for advanced or metastatic disease.

    View Study on ClinicalTrials.gov →

  2. Study: A clinical trial for individuals who have been diagnosed with HR+, HER2-negative advanced breast cancer and have received certain 2 or less previous treatments for their advanced or metastatic breast cancer, as well as treatment with a CDK4/6 inhibitor, such as palbociclib, ribociclib or abemaciclib
    Cancer Type: Breast Cancer
    Study Type/Phase: Interventional / Phase 3
    Principal Investigator: Dr. Lynn R. Kong M.D. FACP

    About this study:
    The purpose of this study is to learn about the safety and effects of the study medicine PF-07248144 when given along with fulvestrant for the possible treatment of HR-positive, HER2-negative advanced or metastatic breast cancer.

    View Study on ClinicalTrials.gov →

  3. Study: Molecular Residual Disease in Solid Tumors: A Prospective Study to Collect Clinical Data and Biospecimens to Support Discovery and Development of Cancer Biomarkers
    Cancer Type: Specific Solid Tumors
    Study Type: Observational
    Principal Investigator: Dr. Lynn R. Kong M.D. FACP

    About this study:
    Have you recently been diagnosed with cancer and is surgery planned as part of your treatment? You may be eligible to participate in a research study. This study is looking to help scientists develop new blood tests to: Detect cancer early, Track how cancer treatment is working, Check for early signs of cancer recurrence, Help future patients with cancer.

    View Study on ClinicalTrials.gov →

Interested in a study?
Talk with your treating physician or contact our research team at 805-485-8709 extension 129 or research@venturaoncology.com. Additional eligibility criteria apply, and listing a study here does not guarantee enrollment.

What is a clinical trial?

A clinical trial is a research study involving people. Clinical trials may evaluate new medications, combinations of treatments, treatment strategies, diagnostic approaches, or other ways to improve patient care.

Some studies are interventional, meaning participants receive a treatment or intervention according to the study protocol. Others are observational, meaning researchers collect and study information without assigning a specific treatment.

What do the phases mean?

Phase 1
Focuses mainly on safety, dosing, and how a new treatment behaves in the body.

Phase 2
Evaluates how well the treatment may work while continuing to study its safety.

Phase 3
Usually compares a new treatment or approach with the current standard treatment in a larger group of patients.

Phase 4
Takes place after a treatment has been approved and studies its use in a broader population.

Some oncology studies combine phases, such as Phase 1/2, within the same clinical trial.

Why do we need clinical trials?

Nearly every treatment used in cancer care today was studied through clinical research.

Clinical trials help researchers determine whether new treatments are safe and effective, identify which patients may benefit most, compare new approaches with existing treatments, and improve future standards of care.

For some patients, a clinical trial may also provide access to a treatment or treatment strategy that is not otherwise available.

Frequently Asked Questions

1. Is participation in a clinical trial free?

Not necessarily.

The study sponsor generally pays for research-specific procedures, tests, or treatments that are required only because of the clinical trial. Routine medical care that you would normally receive may still be billed to you or your health insurance.

Costs vary by study. Before you decide to participate, the research team will explain what the study covers and whether there may be any costs to you.

2. Will participating affect my regular cancer care?

Your treating physician remains involved in your care throughout the clinical trial.

Participating in a study does not take away your right to receive appropriate medical care. Your research and clinical teams work together to coordinate your treatment and monitor your health.

3. Can I leave a clinical trial after I join?

Yes.

Participation is completely voluntary. You may decide to stop participating at any time.

Choosing not to participate - or deciding to withdraw later - will not affect your relationship with your physician or your access to appropriate standard medical care.

Your research team may discuss the safest way to stop study treatment and whether any follow-up is recommended.

4. What happens before I join a clinical trial?

Before enrolling, the research team will explain the study to you through the informed consent process.

You will receive information about:

  • Why the study is being conducted

  • What treatment or procedures are involved

  • Possible risks and side effects

  • Possible benefits

  • Other available treatment options

  • Your rights as a research participant

  • Any study-related costs or reimbursements

  • Who to contact with questions

You will have time to ask questions before deciding whether to participate.

Signing a consent form does not take away your right to change your mind later.

 

5. How do I know if I am eligible?

Every clinical trial has specific eligibility criteria based on factors such as cancer type, stage, prior treatments, laboratory results, tumor characteristics, overall health, and other medical considerations.

Your oncologist and the research team can review your medical history to determine whether a study may be appropriate for you.

 

6. Should I participate in a clinical trial?

There is no single answer that is right for every patient.

A clinical trial may provide access to a promising treatment or help advance cancer care, but investigational treatments can also have unknown risks and may or may not be more effective than standard treatment.

Your decision should be based on a discussion with your physician and research team, your treatment options, your goals and preferences, and your understanding of the study.

You should feel comfortable asking as many questions as you need before making a decision.

 

7. Will I receive a placebo?

Many cancer clinical trials do not use a placebo alone when an effective standard treatment is available.

If a study includes a placebo, that will be clearly explained to you during the informed consent process before you decide whether to participate.

 

8. What are the possible benefits and risks?

Possible benefits may include access to a new treatment or closer study-related monitoring. However, there is no guarantee that an investigational treatment will benefit you.

Possible risks may include side effects, additional appointments or testing, inconvenience, or the possibility that the treatment may not work as expected. The known risks and potential benefits of a specific study will be reviewed with you before enrollment.

 

9. How is my privacy protected?

Clinical trials are required to follow privacy and research regulations designed to protect participants and their medical information.

The consent form will explain what information is collected, who may review it, and how it may be used for the study.

 

Interested in Learning More?

If you would like to know whether one of our clinical trials may be an option for you, please speak with your treating physician or contact our Clinical Research Team.

Clinical Research Team
Phone: 805-485-8709 extension 129
Email: research@venturaoncology.com

You do not need to decide immediately. Asking about a clinical trial does not commit you to participating.